An experimental drug for Alzheimer regenerates teeth affected by cavities or accidents

If so far caries and dental work have irreversibly affected the structure of teeth, this is about to change. Researchers at King's College London have released a study that supports the discovery of a drug that helps restore the bone tissue of the tooth after it has been affected by caries or dental fractures. British researchers have found that an experimental drug for Alzheimer's, called Tideglusib, has as a secondary effect the restoration of the dentin, the bone part of the tooth, made up of calcified tissue (basically the part under the enamel). This extremely simple method can be used in a variety of dental procedures. The drug will appear on the market in a relatively short time, says study author Paul Sharp. Tideglusib, used in clinical trials as a drug for neurological disorders, has the effect of stimulating neuronal cells in the growth process, but as it has been found, it also stimulates the teeth to produce more stem cells that regenerate dentin in areas exposed by problems .

Normally, an extremely thin layer of dentin will grow over a lesion, or far enough to save a severely damaged tooth. When Tideglusib is applied to the affected part of the tooth, it blocks the enzyme that prevents the dentin from growing and thus the whole area is regenerated completely. Photo: pixabay. .